Prophylaxis of intranasally induced pollen allergy in a BALB/C mouse model using a potential prebiotic β-1, 4 mannobiose.

@article{Yang2013ProphylaxisOI,
  title={Prophylaxis of intranasally induced pollen allergy in a BALB/C mouse model using a potential prebiotic β-1, 4 mannobiose.},
  author={Chengbo Yang and Prithy Rupa and Hiroyuki Kanatani and Akihiro Nakamura and Masahisa Ibuki and Yoshinori Mine},
  journal={Allergology international : official journal of the Japanese Society of Allergology},
  year={2013},
  volume={62 1},
  pages={53-64}
}
BACKGROUND Dietary supplementation with unique prebiotic nondigestible carbohydrates has been shown to suppress allergy. In the present study, the prophylactic efficacy of a disaccharide β-1, 4 mannobiose (MNB) in a BALB/C mouse model of intranasally-induced pollen allergy was characterized. METHODS Balb/c mice were pretreated with MNB orally and… CONTINUE READING