Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats.

Abstract

Lipopolysaccharide (LPS), a component of the cell wall of Gram-negative bacteria, stimulates phagocytes to generate metabolites that play an important role in the pathogenesis of acute lung injury. In this study, the prophylactic effect of liposome-entrapped dexamethasone (L-DEX) was evaluated in an animal acute lung injury model. Rats were pretreated… (More)

Topics

  • Presentations referencing similar topics