Prophylactic use of pentoxifylline on inflammation in elderly cardiac surgery patients.

@article{Boldt2001ProphylacticUO,
  title={Prophylactic use of pentoxifylline on inflammation in elderly cardiac surgery patients.},
  author={Joachim Boldt and Christian Brosch and Andreas Lehmann and G{\"u}nther Haisch and Johannes Lang and Frank Isgro},
  journal={The Annals of thoracic surgery},
  year={2001},
  volume={71 5},
  pages={1524-9}
}
BACKGROUND Inflammation plays a pivotal role in the pathogenesis of organ injury after cardiopulmonary bypass (CPB). Elderly patients appear to be especially prone to develop general inflammation. Use of pentoxifylline (PTX) before surgery may be a promising approach to minimize the negative effects of CPB in these patients. METHODS In a prospective, randomized study, patients more than 80 years old undergoing aortocoronary artery bypass grafting received either PTX (n = 15) after induction… CONTINUE READING

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