Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate

@article{Kouides2001ProphylacticTO,
  title={Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate},
  author={P. Kouides and L. Kulzer},
  journal={Haemophilia},
  year={2001},
  volume={7}
}
Factor X (FX) deficiency is an autosomal recessive trait that occurs in fewer than 1 in 500 000 people. Not surprisingly, reports of prophylactic treatment for FX deficiency are exceedingly rare. We now report our experience of the use of prophylactic therapy in a FX‐deficient patient. This 18‐year‐old African‐American male presented at the age of 4½ years with an FX level < 1%. Treatment was on demand with prothrombin complex concentrates (PCCs) given at two times the dose per kilogram of body… Expand
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