Prophylactic therapy with lithium in elderly patients with unipolar major depression.

@article{Wilkinson2002ProphylacticTW,
  title={Prophylactic therapy with lithium in elderly patients with unipolar major depression.},
  author={David G Wilkinson and Clive Holmes and Janet Woolford and Susan Stammers and Janine North},
  journal={International journal of geriatric psychiatry},
  year={2002},
  volume={17 7},
  pages={
          619-22
        }
}
OBJECTIVES To compare the relapse rate of elderly depressed patients taking low dose lithium as an additional therapy with antidepressant medication to those receiving antidepressant medication alone. METHODS Fifty elderly subjects recovering from a major depressive illness taking continuation antidepressants were randomised, in a double blind study, to receive additional lithium carbonate or placebo and followed up over a two year period for evidence of relapse. RESULTS Relapse rate was… CONTINUE READING
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