Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors.

@article{Young2005ProphylacticRF,
  title={Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors.},
  author={Guy Aaron Young and Michael R Mcdaniel and Diane Jean Nugent},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2005},
  volume={11 3},
  pages={
          203-7
        }
}
Prevention of bleeding, especially into joints, with prophylactic factor infusions is the most effective treatment for severe haemophilia patients. Approximately 15-30% of patients with factor VIII deficiency and 3-5% of patients with factor IX deficiency develop neutralizing antibodies (inhibitors) to factor precluding their use. Such patients often have significant bleeding complications including life- and limb-threatening bleeds and severe joint disease. Prophylaxis for such patients is not… CONTINUE READING
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