Prophylactic oral/topical non-absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants.

@article{Austin2009ProphylacticON,
  title={Prophylactic oral/topical non-absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants.},
  author={Nicola C Austin and Brian Alexander Darlow and William McGuire},
  journal={The Cochrane database of systematic reviews},
  year={2009},
  volume={4},
  pages={CD003478}
}
BACKGROUND Invasive fungal infection is an important cause of mortality and morbidity in very preterm (< 32 weeks gestation) or very low birth weight (VLBW) infants. Clinical uncertainly exists about the effect of prophylactic oral/topical non-absorbed antifungals to reduce mucocutaneous colonisation and so limit the risk of invasive fungal infection in this population. OBJECTIVES To assess the effect of prophylactic oral/topical non-absorbed antifungal therapy on the incidence of invasive… CONTINUE READING
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