Prophylactic intraperitoneal povidone-iodine in alimentary tract surgery.

  title={Prophylactic intraperitoneal povidone-iodine in alimentary tract surgery.},
  author={O J Gilmore and Cheryl M. Reid and Elizabeth T S Houang and Elizabeth J. Shaw},
  journal={American journal of surgery},
  volume={135 2},
In controlled experiments intraperitoneal povidone-iodine significantly reduced the mortality of mice (p less than 0.01) and rats (p less than 0.01) with induced peritonitis. Povidone-iodine irrigation of the rat colon before and after anastomosis did not interfere with healing or inhibit peritoneal adhesion formation. However, a newly formulated povidone-iodine solution containing increased PVP significantly reduced adhesion formation in a controlled study in rats. 

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