Prophylactic hepatic arterial infusion chemotherapy for the prevention of liver metastasis in patients with colon carcinoma: a randomized control trial.

@article{Sadahiro2004ProphylacticHA,
  title={Prophylactic hepatic arterial infusion chemotherapy for the prevention of liver metastasis in patients with colon carcinoma: a randomized control trial.},
  author={Sotaro Sadahiro and Toshiyuki Suzuki and Kenji Ishikawa and Seiei Yasuda and Tomoo Tajima and Hiroyasu Makuuchi and Takuro Saitoh and Chieko Murayama},
  journal={Cancer},
  year={2004},
  volume={100 3},
  pages={590-7}
}
BACKGROUND The liver is the most frequent site of recurrence after curative resection in patients with colon carcinoma. For liver metastasis, a high response rate can be achieved with hepatic arterial infusion (HAI) chemotherapy. In the current study, the authors administered 5-fluorouracil (5-FU) as adjuvant chemotherapy by HAI to patients with colon carcinoma without liver metastases and studied its effects on recurrence in the liver and survival. METHODS A total of 316 patients with… CONTINUE READING
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