Prophylactic effect of monensin sodium against experimentally induced paratuberculosis in mice.

@article{Brumbaugh1992ProphylacticEO,
  title={Prophylactic effect of monensin sodium against experimentally induced paratuberculosis in mice.},
  author={Gordon W Brumbaugh and P F Frelier and Allen J Roussel and T D Thomson},
  journal={American journal of veterinary research},
  year={1992},
  volume={53 4},
  pages={544-6}
}
Monensin sodium (0, 15, or 30 mg/kg of complete feed) was fed ad libitum for 1 week to female mice (strain C57BL6/J) that were genetically susceptible to infection with Mycobacterium paratuberculosis. Ten mice in each of the 3 groups were inoculated intraperitoneally with M paratuberculosis (10(9) organisms). Sterile saline solution was injected intraperitoneally into 10 other mice in each group. Rations were continued for 50 days, then mice were euthanatized, and body weight, splenic weight… CONTINUE READING

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