Prophylactic effect of antivaccinia gamma-globulin against post-vaccinal encephalitis.

  title={Prophylactic effect of antivaccinia gamma-globulin against post-vaccinal encephalitis.},
  author={W. Nanning},
  journal={Bulletin of the World Health Organization},
  • W. Nanning
  • Published 1962 in Bulletin of the World Health Organization
In the Netherlands, the frequency of encephalitis after smallpox vaccination is estimated to be 1 in 4000 primary vaccinations in adults and 1 in 50 000 revaccinations. Since immunity seems to reduce the frequency of this complication, it was thought that it might be possible to prevent post-vaccinal encephalitis by a combination of passive and active immunization, a basic immunity being obtainable without risk by the injection of antivaccinia gamma-globulin (AGG). This theory was tested in… CONTINUE READING

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