Prophylactic antiemetic efficacy of granisetron or ramosetron in patients undergoing thyroidectomy.

@article{Lee2002ProphylacticAE,
  title={Prophylactic antiemetic efficacy of granisetron or ramosetron in patients undergoing thyroidectomy.},
  author={Soo Young Lee and Joo Yong Lee and Sang Youn Park and Joo Hyung Kim and O G Cho and Ju Sung Kim and Euy Young Soh},
  journal={Asian journal of surgery},
  year={2002},
  volume={25 4},
  pages={309-14}
}
OBJECTIVE Thyroidectomy is associated with a high incidence of postoperative nausea and vomiting (PONV), ranging from 60% to 84%. We conducted this study to compare the antiemetic effects and safety of granisetron 20 micro g/kg and ramosetron 4 micro g/kg in patients undergoing elective thyroidectomy under standard anaesthetic technique. METHODS One hundred and thirteen patients were randomized to receive placebo (n = 41), granisetron 20 nug/kg (n = 36) or ramosetron 4 micro g/kg (n = 36… CONTINUE READING