Prophylactic action of linseed (Linum usitatissimum) oil against cyclophosphamide-induced oxidative stress in mouse brain.

@article{Bhatia2006ProphylacticAO,
  title={Prophylactic action of linseed (Linum usitatissimum) oil against cyclophosphamide-induced oxidative stress in mouse brain.},
  author={Arvind Lal Bhatia and Kailash Manda and Shikha Patni and Antim Lata Sharma},
  journal={Journal of medicinal food},
  year={2006},
  volume={9 2},
  pages={261-4}
}
The present study is a pilot study that explores the antioxidative properties of linseed (Linum usitatissimum) oil in its prophylactic action against oxidative stress induced by a radiomimetic drug, cyclophosphamide. Oral administration of linseed oil (0.1 mL/kg of body weight/day) for 20 days prior to an acute dose of cyclophosphamide (75 mg/kg) significantly inhibited the augmented level of malondialdehyde, conjugated dienes, and hydroperoxides in the mouse brain. The cyclophosphamide… CONTINUE READING