Prophylactic actinomycin D for high-risk complete hydatidiform mole.

  title={Prophylactic actinomycin D for high-risk complete hydatidiform mole.},
  author={Sompop Limpongsanurak},
  journal={The Journal of reproductive medicine},
  volume={46 2},
OBJECTIVE To evaluate the effectiveness of one course of prophylactic actinomycin D in reducing the malignant sequelae requiring chemotherapy in high-risk complete hydatidiform mole (CHM). STUDY DESIGN A double-blind, randomized, controlled clinical trial was carried out at King Chulalongkorn Memorial Hospital. Sixty cases of CHM classified as high risk were recruited and randomly allocated to a chemoprophylactic or control group. Within one week after evacuation of molar tissues, actinomycin… CONTINUE READING


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