Prophylactic Use of Macrolide Antibiotics for the Prevention of Chronic Obstructive Pulmonary Disease Exacerbation: A Meta-Analysis

@inproceedings{Ni2015ProphylacticUO,
  title={Prophylactic Use of Macrolide Antibiotics for the Prevention of Chronic Obstructive Pulmonary Disease Exacerbation: A Meta-Analysis},
  author={Wentao Ni and Xiaodi Shao and Xuejiu Cai and Chuanqi Wei and Junchang Cui and Rui Wang and You-ning Liu},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) can lead to high frequencies and rates of hospitalization and mortality. Macrolides are a class of antibiotics that possess both antimicrobial and anti-inflammatory properties. Since the occurrence of AECOPDs is associated with aggravation of airway inflammation and bacterial infections, prophylactic macrolide treatment may be an effective approach towards the prevention of AECOPDs. METHODS We systemically… CONTINUE READING
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