Prophage-mediated defence against viral attack and viral counter-defence

  title={Prophage-mediated defence against viral attack and viral counter-defence},
  author={Rebekah M. Dedrick and Deborah Jacobs-Sera and C. Bustamante and Rebecca A. Garlena and Travis N. Mavrich and Welkin H Pope and Juan C. Cervantes Reyes and Daniel A. Russell and Tamarah L. Adair and Richard M Alvey and J. Alfred Bonilla and Jerald S. Bricker and Bryony R. Brown and Deanna Byrnes and Steven G. Cresawn and William B. Davis and Leon A. Dickson and Nicholas P. Edgington and Ann M. Findley and Urszula P. Golebiewska and Julianne H. Grose and Cory F. Hayes and Lee E. Hughes and Keith W. Hutchison and Sharon Isern and Allison A Johnson and Margaret A. Kenna and Karen Klyczek and Catherine M. Mageeney and Scott F. Michael and Sally D. Molloy and Matthew T. Montgomery and James Neitzel and Shallee T. Page and Marie C Pizzorno and Marianne K. Poxleitner and Claire A. Rinehart and Courtney J Robinson and Michael R. Rubin and Joseph N. Teyim and Edwin V{\'a}zquez and Vassie C. Ware and Jacqueline M Washington and Graham F. Hatfull},
  journal={Nature Microbiology},
Temperate phages are common, and prophages are abundant residents of sequenced bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium tuberculosis and Mycobacterium smegmatis, encompass substantial genetic diversity and are commonly temperate. Characterization of ten Cluster N temperate mycobacteriophages revealed at least five distinct prophage-expressed viral defence systems that interfere with the infection of lytic and temperate phages that… CONTINUE READING
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