Properties of voltage-gated potassium currents in nucleated patches from large layer 5 cortical pyramidal neurons of the rat.

@article{Bekkers2000PropertiesOV,
  title={Properties of voltage-gated potassium currents in nucleated patches from large layer 5 cortical pyramidal neurons of the rat.},
  author={John M Bekkers},
  journal={The Journal of physiology},
  year={2000},
  volume={525 Pt 3},
  pages={593-609}
}
Voltage-gated potassium currents were studied in nucleated outside-out patches obtained from large layer 5 pyramidal neurons in acute slices of sensorimotor cortex from 13- to 15-day-old Wistar rats (22-25 C). Two main types of current were found, an A-current (IA) and a delayed rectifier current (IK), which were blocked by 4-aminopyridine (5 mM) and tetraethylammonium (30 mM), respectively. Recovery from inactivation was mono-exponential (for IA) or bi-exponential (for IK) and strongly voltage… CONTINUE READING
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