Properties of the nociceptive neurons of the leech segmental ganglion.

@article{Pastor1996PropertiesOT,
  title={Properties of the nociceptive neurons of the leech segmental ganglion.},
  author={Jes{\'u}s Naval{\'o}n Pastor and B. Soria and Carlos Belmonte},
  journal={Journal of neurophysiology},
  year={1996},
  volume={75 6},
  pages={
          2268-79
        }
}
1. The electrical responses of nociceptive (N) lateral and N medial neurons of the leech segmental ganglion to mechanical, chemical, and thermal stimulation of the skin were studied in a superfused ganglion-body wall preparation. 2. Mechanical indentation of the skin > 10 mN evoked in both types of cells a sustained discharge of impulses; afterdischarge was often observed with suprathreshold stimulations. 3. Application to the cutaneous receptive area of 10-100 mM acetic acid or of NaCI… Expand
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Following injection of horseradish peroxidase into the soma, axons of N cells appear as unspecialized fine processes about 1 micrometer in diameter, in the dermis of the leech, deep to the layer of epidermal cells. Expand
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The effects of the local anesthetic, procaine, on the electrophysiological properties of the leech neurons responding to nociceptive stimuli (N cells) were examined in isolated segmental ganglia in Macrobdella and it seems likely that an increase in the resting K conductance was a contributing factor to this hyperpolarization. Expand
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