Properties of the K562 cell line, derived from a patient with chronic myeloid leukemia.

@article{Klein1976PropertiesOT,
  title={Properties of the K562 cell line, derived from a patient with chronic myeloid leukemia.},
  author={Eva Klein and H Ben-bassat and Hava Neumann and Peter Ralph and Jesper Zeuthen and Aaron Polliack and Farkas V{\'a}nky},
  journal={International journal of cancer},
  year={1976},
  volume={18 4},
  pages={421-31}
}
The K562 cell line derived from a CML patient in blast crisis was examined for properties of B and T lymphocytes and cell lines. K562 lacks the B markers of immunoglobulins, Epstein-Barr virus (EBV) genome and associated nuclear antigen, and receptors for EBV. A low proportion of cells from rosettes with sheep erythrocytes, the frequency of which is considerably increased after neuraminidase treatment. Unlike B lines but like T lines, K562 cells are lysed rapidly by C'/Fc receptor-positive… CONTINUE READING