Properties of somatic cell hybrids between mouse cells and simian virus 40-transformed rat cells.

Abstract

Hybrids between mouse cells and simian virus 40 (SV40)-transformed rat cells were made, and their properties and chromosome constitution were investigated over many generations. Their hybrid nature was confirmed by enzyme studies. During a period of 1 year a loss of 10 to 20% of the total number of chromosomes was observed. The SV40 tumor antigen was… (More)

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@article{Noordaa1972PropertiesOS, title={Properties of somatic cell hybrids between mouse cells and simian virus 40-transformed rat cells.}, author={J. van der Noordaa and A van Haagen and J M M Walboomers and H V van Someren}, journal={Journal of virology}, year={1972}, volume={10 1}, pages={67-72} }