Properties of bacteriophage T4 mutants defective in DNA polymerase.

G E N E 43 of bacteriophage T4 resides at approximately 320" on the standard map ( STAHL, EDGAR and STEINBERG 1964). Studies of temperatwe-sensitive ( t s ) and amber (am) mutants reveal that gene 43 is the structural gene for the viral DNA polymerase (DE WAARD, PAUL and LEHMAN 1965; WARNER and BARNES 1966; NOSSAL 1969). The T4 DNA polymerase resembles the… CONTINUE READING