Properties of a distal regulatory element controlling transcription of the U2 small nuclear RNA.

@article{Westin1987PropertiesOA,
  title={Properties of a distal regulatory element controlling transcription of the U2 small nuclear RNA.},
  author={Gunnar Westin and J. Zabielski and L. Janson and U. Pettersson},
  journal={Gene},
  year={1987},
  volume={59 2-3},
  pages={183-90}
}
The upstream region of human U2 genes contains a distal transcriptional control element, previously mapped between nucleotide (nt) positions -198 and -258 (Westin et al., 1984b). In the present study we show that it resembles transcriptional enhancers in being active even from a distance of 1.4 kb. However, in contrast to most other enhancers it functions unidirectionally in Xenopus laevis oocytes. The distal control element was further mapped by construction of truncated templates for U2 RNA… CONTINUE READING
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