Properties of Protein Drug Target Classes

  title={Properties of Protein Drug Target Classes},
  author={Simon C. Bull and Andrew J. Doig},
  booktitle={PloS one},
Accurate identification of drug targets is a crucial part of any drug development program. We mined the human proteome to discover properties of proteins that may be important in determining their suitability for pharmaceutical modulation. Data was gathered concerning each protein's sequence, post-translational modifications, secondary structure, germline variants, expression profile and drug target status. The data was then analysed to determine features for which the target and non-target… CONTINUE READING
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