Properties of 3-hydroxypropionaldehyde 3-phosphate.

  title={Properties of 3-hydroxypropionaldehyde 3-phosphate.},
  author={A. Gallopo and W. Cleland},
  journal={Archives of biochemistry and biophysics},
  volume={195 1},
Abstract Several modifications to the synthesis of the diethyl acetal of 3-hydroxypropionaldehyde-3-P (HPAP) are described. HPAP is liberated from its acetal by treatment with Dowex 50-H + at 40 °C for 4 min, and longer time or higher temperature lower yields. Breakdown of the dianion of HPAP (p K 6.7) is self-catalyzed, with the phosphate acting as a general base to remove a proton from carbon 2 and allow elimination of phosphate to give acrolein. Monoanion breakdown is at least 400-fold… Expand
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