Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration

@article{Suzuki2012PropertiesAU,
  title={Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration},
  author={S. Suzuki and T. Muneta and K. Tsuji and S. Ichinose and H. Makino and A. Umezawa and I. Sekiya},
  journal={Arthritis Research \& Therapy},
  year={2012},
  volume={14},
  pages={R136 - R136}
}
IntroductionTransplantation of mesenchymal stem cells (MSCs) derived from synovium is a promising therapy for cartilage regeneration. For clinical application, improvement of handling operation, enhancement of chondrogenic potential, and increase of MSCs adhesion efficiency are needed to achieve a more successful cartilage regeneration with a limited number of MSCs without scaffold. The use of aggregated MSCs may be one of the solutions. Here, we investigated the handling, properties and… Expand
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References

SHOWING 1-10 OF 31 REFERENCES
Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit
Mesenchymal stem cell-based therapy for cartilage repair: a review
Synovial fluid-derived mesenchymal stem cells increase after intra-articular ligament injury in humans.
Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties
BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells.
Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source.
...
1
2
3
4
...