Properties and regulation of the GTPase activities of elongation factors Tu and G, and of initiation factor 2

@article{Parmeggiani2006PropertiesAR,
  title={Properties and regulation of the GTPase activities of elongation factors Tu and G, and of initiation factor 2},
  author={Andrea Parmeggiani and Gernot Sander},
  journal={Molecular and Cellular Biochemistry},
  year={2006},
  volume={35},
  pages={129-158}
}
SummaryDuring protein synthesis the interaction with ribosomes of elongation factors Tu (EF-Tu), G (EF-G) and initiation factor 2 (IF-2) is associated with the hydrolysis of GTP which is directly related to the functions of the factors. In this article we review systematically the properties of these GTPase activities in the presence and absence of protein synthesis, and by examining the characteristics of the different minimal systems for the expression of these activities we point to the role… 

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