Properties, characteristics and applications of microbubbles for sonothrombolysis.

  title={Properties, characteristics and applications of microbubbles for sonothrombolysis.},
  author={Marie de Saint Victor and Calum Crake and C C Coussios and Eleanor Stride},
  journal={Expert opinion on drug delivery},
  volume={11 2},
INTRODUCTION Ultrasound enhancement of thrombolysis (sonothrombolysis) is further potentiated by administration of acoustically active microbubbles, which may be developed into powerful adjuvant therapies for thrombolytic treatment of occlusive conditions such as ischaemic stroke. AREAS COVERED The role of microbubbles in sonothrombolysis is evaluated based on published in vitro and in vivo evidence and a critical review of clinical trials to date. Microbubble, ultrasound and drug parameters… CONTINUE READING
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