Proper usage of pancreatic enzymes.

@article{Schibli2002ProperUO,
  title={Proper usage of pancreatic enzymes.},
  author={Susanne Schibli and Peter R. Durie and Elizabeth D Tullis},
  journal={Current opinion in pulmonary medicine},
  year={2002},
  volume={8 6},
  pages={
          542-6
        }
}
With the recognition of the close link between nutritional status and pulmonary function in cystic fibrosis (CF), treatment and prevention of malnutrition have become a major focus in the modern therapeutic approach for patients with CF. Thereby, pancreatic enzyme replacement therapy plays a central role. This article reviews key publications on important aspects of pancreatic enzyme replacement therapy contained in the literature over the last 12 months. New insights into the pathogenesis of… Expand
Pancreatic Enzyme Pharmacotherapy
TLDR
The delivery of sufficient enzyme concentrations into the duodenal lumen simultaneously with meals can reduce nutrient malabsorption, improve the symptoms of steatorrhea, and in some cases alleviate the pain associated with chronic pancreatitis. Expand
Nutrition in cystic fibrosis.
  • J. Matel, C. Milla
  • Medicine
  • Seminars in respiratory and critical care medicine
  • 2009
TLDR
Aggressive nutritional support with adequate pancreatic replacement management should lead to both normal growth and lung function preservation, and treatment programs that place an emphasis on higher caloric intake and more aggressive nutritional management in CF patients report better outcomes. Expand
Nutrition Management of Cystic Fibrosis in the 21st Century.
TLDR
Clinicians may encounter patients with cystic fibrosis in obstetrician offices, endocrine clinics, or hospital settings, owing to lung transplantation or for treatment for distal intestinal obstruction syndrome. Expand
Pancreatic enzyme replacement therapy for people with cystic fibrosis.
TLDR
The efficacy and safety of pancreatic enzyme replacement therapy in children and adults with cystic fibrosis is evaluated and the efficacy andSafety of different formulations of this therapy and their appropriateness in different age groups are compared. Expand
Pancreatic enzyme replacement therapy for people with cystic fibrosis.
TLDR
There is limited evidence of benefit from enteric-coated microspheres when compared to non-enteric coated pancreatic enzyme preparations up to one month and no evidence on the long-term effectiveness and risks associated with PERT. Expand
Pancreatic enzyme therapy in cystic fibrosis
  • J. Dodge
  • Medicine
  • Expert review of respiratory medicine
  • 2008
TLDR
It is shown that in the preoccupation with control of chronic pulmonary infection, the importance of pancreatic insufficiency can be underestimated. Expand
Pancreatic enzyme replacement therapy for people with cystic fibrosis.
TLDR
A systematic review of randomised and quasi-randomised controlled trials in people of any age, with cystic fibrosis and receiving pancreatic enzyme replacement therapy, at any dosage and in any formulation, for a period of not less than four weeks, found limited evidence of benefit from enteric-coated microspheres when compared to non-enteric coated pancreatic enzymes preparations up to one month. Expand
Pancreatic Enzyme Replacement Therapy and Coefficient of Fat Absorption in Children and Adolescents With Cystic Fibrosis
TLDR
In this study population, no correlation between an enzyme dosage and the degree of fat malabsorption was found; however, a CFA below 85% was found in 24% of the measurements. Expand
Introduction: raising awareness of pancreatic exocrine insufficiency - does your patient need enzyme supplementation?
TLDR
Chronic pancreatitis is a chronic disease that affects patients in the UK in diverse ways and is frequently made rather late in the course of the disease. Expand
Review article: enzyme supplementation in cystic fibrosis, chronic pancreatitis, pancreatic and periampullary cancer
TLDR
This paper focuses on the treatment of chronic pancreatitis, a major complication of pancreatic exocrine insufficiency, which is frequently made rather late in the course of the disease. Expand
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