Proper interpretation of non-differential misclassification effects: expectations vs observations.

  title={Proper interpretation of non-differential misclassification effects: expectations vs observations.},
  author={Anne M. Jurek and Sander Greenland and George Maldonado and Timothy Robert Church},
  journal={International journal of epidemiology},
  volume={34 3},
BACKGROUND Many investigators write as if non-differential exposure misclassification inevitably leads to a reduction in the strength of an estimated exposure-disease association. Unfortunately, non-differentiality alone is insufficient to guarantee bias towards the null. Furthermore, because bias refers to the average estimate across study repetitions rather than the result of a single study, bias towards the null is insufficient to guarantee that an observed estimate will be an underestimate… CONTINUE READING
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