Propensity for social interaction predicts nicotine-reinforced behaviors in outbred rats.

@article{Wang2014PropensityFS,
  title={Propensity for social interaction predicts nicotine-reinforced behaviors in outbred rats.},
  author={T Wang and Wenyan Han and Benhan Wang and Q Jiang and Leah Solberg-Woods and Abraham A Palmer and H Chen},
  journal={Genes, brain, and behavior},
  year={2014},
  volume={13 2},
  pages={202-12}
}
Social and genetic factors can influence smoking behavior. Using olfactogustatory stimuli as the sensory cue for intravenous nicotine self-administration (SA), we previously showed that social learning of nicotine contingent odor cue prevented rats from developing conditioned taste aversion and allowed them to instead establish stable nicotine SA. We hypothesized that genetic factors influenced socially acquired nicotine SA. A heterogeneous stock (HS; N/NIH) of outbred rats was trained to self… CONTINUE READING
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