Propagation of vasomotor responses coordinates arteriolar resistances.

  title={Propagation of vasomotor responses coordinates arteriolar resistances.},
  author={Steven S Segal and David N Damon and Brian R. Duling},
  journal={The American journal of physiology},
  volume={256 3 Pt 2},
We tested the hypothesis that a conduction pathway intrinsic to the arteriolar wall possesses the properties necessary to coordinate vasomotor responses in the microcirculation. Acetylcholine (ACh) or norepinephrine (NE) was iontophoresed onto cheek pouch arterioles (15-35 microns diam) of pentobarbital-anesthetized hamsters, and diameter responses were observed using intravital video microscopy. ACh and NE induced vasodilation and vasoconstriction, respectively, that propagated both upstream… CONTINUE READING


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