Propagation of slow waves requires IP3 receptors and mitochondrial Ca2+ uptake in canine colonic muscles.

@article{Ward2003PropagationOS,
  title={Propagation of slow waves requires IP3 receptors and mitochondrial Ca2+ uptake in canine colonic muscles.},
  author={Sean M Ward and Salah A Baker and Andrew de Faoite and Kenton M. Sanders},
  journal={The Journal of physiology},
  year={2003},
  volume={549 Pt 1},
  pages={
          207-18
        }
}
In the gastrointestinal (GI) tract electrical slow waves yield oscillations in membrane potential that periodically increase the open probability of voltage-dependent Ca2+ channels and facilitate phasic contractions. Slow waves are generated by the interstitial cells of Cajal (ICC), and these events actively propagate through ICC networks within the walls of GI organs. The mechanism that entrains spontaneously active pacemaker sites throughout ICC networks to produce regenerative propagation of… CONTINUE READING
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