Propagation of pacemaker activity

@article{Joyner2006PropagationOP,
  title={Propagation of pacemaker activity},
  author={Ronald W. Joyner and Ronald Wilders and Mary B. Wagner},
  journal={Medical & Biological Engineering & Computing},
  year={2006},
  volume={45},
  pages={177-187}
}
Spontaneous activity of specific regions (e.g., the Sinoatrial node, SAN) is essential for the normal activation sequence of the heart and also serve as a primary means of modulating cardiac rate by sympathetic tone and circulating catecholamines. The mechanisms of how a small SAN region can electrically drive a much larger atrium, or how a small ectopic focus can drive surrounding ventricular or atrial tissue are complex, and involve the membrane properties and electrical coupling within the… CONTINUE READING

Citations

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  • 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
  • 2015
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Temporo-Spatial Model Construction Using the MML and Software Framework

  • IEEE Transactions on Biomedical Engineering
  • 2011
VIEW 1 EXCERPT
CITES BACKGROUND

Focal atrial tachycardia: increased electrogram fractionation in the vicinity of the earliest activation site.

  • Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2008
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

insights from a mathematical model

M Courtemanche, RJ Ramirez, properties Nattel S Ionic mechanisms underlying human atrial potential
  • Am J Physiol 275(1 Pt 2):H301–H321 186 Med Bio Eng Comput
  • 2007
VIEW 1 EXCERPT

Structure-function relationship in the AV junction.

  • The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology
  • 2004
VIEW 1 EXCERPT