Propagation of cortical spreading depolarization in the human cortex after malignant stroke.

@article{Woitzik2013PropagationOC,
  title={Propagation of cortical spreading depolarization in the human cortex after malignant stroke.},
  author={Johannes Woitzik and N. K. Hecht and Alexandra Pinczolits and Nora Sandow and Sebastian Major and Maren K L Winkler and Steffen Weber-Carstens and Christian Dohmen and Rudolf Graf and Anthony J. Strong and Jens P Dreier and Peter Vajkoczy},
  journal={Neurology},
  year={2013},
  volume={80 12},
  pages={1095-102}
}
OBJECTIVE To investigate hemodynamic response pattern and spatiotemporal propagation of cortical spreading depolarization in the peri-infarct region of malignant hemispheric stroke. METHODS In this prospective observational case study we used intraoperative laser speckle technology to measure cerebral blood flow in patients with malignant hemispheric stroke. Additionally, postoperative occurrence of cortical spreading depolarization was monitored using a subdural recording strip for… CONTINUE READING
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