Propagation and differentiation of human Wharton's jelly stem cells on three-dimensional nanofibrous scaffolds.

@article{Gauthaman2013PropagationAD,
  title={Propagation and differentiation of human Wharton's jelly stem cells on three-dimensional nanofibrous scaffolds.},
  author={K. Gauthaman and Chong Hui Ann Fong and Jayarama Reddy Venugopal and Arijit Biswas and Seeram Ramakrishna and Ariff Bongso},
  journal={Methods in molecular biology},
  year={2013},
  volume={1058},
  pages={
          1-23
        }
}
Stem cells isolated from the Wharton's jelly of the human umbilical cord (hWJSCs) are unique compared to other stem cell types as they lie in between embryonic stem cells (ESCs) and adult mesenchymal stem cells (MSCs) on the developmental map and share stemness markers of ESCs and MSCs. Yet, they do not induce tumorigenesis and are hypoimmunogenic and proliferative and fresh cell numbers can be harvested painlessly in abundance from discarded umbilical cords. Additionally, they secrete… CONTINUE READING
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