Proopiomelanocortin production by epidermal cells: evidence for an immune neuroendocrine network in the epidermis

@article{Bhardwaj2004ProopiomelanocortinPB,
  title={Proopiomelanocortin production by epidermal cells: evidence for an immune neuroendocrine network in the epidermis},
  author={R. Bhardwaj and T. Luger},
  journal={Archives of Dermatological Research},
  year={2004},
  volume={287},
  pages={85-90}
}
Proopiomelanocortin (POMC) is known to be synthesized in the pituitary gland and is subsequently cleaved by specific prohormone convertases into biologically active peptide hormones such as melanocyte stimulating hormones (MSH), adrenocorticotropin (ACTH) and endorphins (EP). Guanine nucleotide-binding protein (G-protein)-coupled receptors, which have only recently been discovered, are involved in the transmission of their message. There is also evidence indicating that POMC is not only… Expand
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