Proof-of-principle for SERS imaging of Aspergillus nidulans hyphae using in vivo synthesis of gold nanoparticles.

@article{Prusinkiewicz2012ProofofprincipleFS,
  title={Proof-of-principle for SERS imaging of Aspergillus nidulans hyphae using in vivo synthesis of gold nanoparticles.},
  author={Martin A. Prusinkiewicz and Fatemeh Farazkhorasani and James J. Dynes and Jian Wang and Kathleen M. Gough and Susan G W Kaminskyj},
  journal={The Analyst},
  year={2012},
  volume={137 21},
  pages={
          4934-42
        }
}
High spatial resolution methods to assess the physiology of growing cells should permit analysis of fungal biochemical composition. Whole colony methods cannot capture the details of physiology and organism-environment interaction, in part because the structure, function and composition of fungal hyphae vary within individual cells depending on their distance from the growing apex. Surface Enhanced Raman Scattering (SERS) can provide chemical information on materials that are in close contact… 

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