Pronounced weight gain in insulin-treated patients with type 2 diabetes mellitus is associated with an unfavourable cardiometabolic risk profile.

@article{Jansen2010PronouncedWG,
  title={Pronounced weight gain in insulin-treated patients with type 2 diabetes mellitus is associated with an unfavourable cardiometabolic risk profile.},
  author={Henry J. Jansen and Gerald M. M. Vervoort and Marinette van der Graaf and Cees J.J. Tack},
  journal={The Netherlands journal of medicine},
  year={2010},
  volume={68 11},
  pages={359-66}
}
Pronounced weight gain after start of insulin therapy in patients with type 2 diabetes mellitus (T2DM) may offset beneficial effects conferred by the improvement of glycaemic control. This hypothesis was tested by comparing the cardiometabolic risk profile of a group of type 2 diabetes patients with a marked increase in body weight ('gainers) after the start of insulin treatment and a similar group without any or only minimal weight gain ('non-gainers'). In a cross-sectional study, we compared… CONTINUE READING
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