Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials.

@article{Ahrn2014PronouncedRO,
  title={Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials.},
  author={Bo Ahr{\'e}n and J-F Gautier and Rachele Berria and William H. Stager and Ronnie Aronson and Clifford J Bailey},
  journal={Diabetes, obesity & metabolism},
  year={2014},
  volume={16 9},
  pages={
          861-8
        }
}
AIM Glucagon-like peptide-1 (GLP-1) receptor agonists improve islet function and delay gastric emptying in patients with type 2 diabetes mellitus (T2DM). This meta-analysis aimed to investigate the effects of the once-daily prandial GLP-1 receptor agonist lixisenatide on postprandial plasma glucose (PPG), glucagon and insulin levels. METHODS Six randomized, placebo-controlled studies of lixisenatide 20 µg once daily were included in this analysis: lixisenatide as monotherapy (GetGoal-Mono… CONTINUE READING
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