Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: a nationwide study.

@article{Towfighi2010PronouncedAO,
  title={Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: a nationwide study.},
  author={Amytis Towfighi and Daniela Markovic and Bruce I Ovbiagele},
  journal={Journal of the neurological sciences},
  year={2010},
  volume={298 1-2},
  pages={153-7}
}
BACKGROUND Although the original homocysteine hypothesis for atherothrombotic disease is falling out of favor, prior studies did not comprehensively adjust for confounders or explore specific subgroups of patients who may benefit from serum homocysteine-lowering. We aimed to determine (1) if elevated total homocysteine (tHcy) affects odds of prevalent stroke after adjusting for a broad array of pertinent covariates and (2) whether particular vascular risk factors amplify the effect of high… CONTINUE READING

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