Pronociceptive pain modulation in patients with painful chemotherapy-induced polyneuropathy.

  title={Pronociceptive pain modulation in patients with painful chemotherapy-induced polyneuropathy.},
  author={Hadas Nahman-Averbuch and David Yarnitsky and Yelena Granovsky and Elliot Sprecher and Mariana Steiner and Tzahala Tzuk-Shina and Dorit Pud},
  journal={Journal of pain and symptom management},
  volume={42 2},
CONTEXT Several chemotherapy agents induce polyneuropathy that is painful for some patients, but not for others. We assumed that these differences might be attributable to varying patterns of pain modulation. OBJECTIVES The aim of the present study was to evaluate pain modulation in such patients. METHODS Twenty-seven patients with chemotherapy-induced polyneuropathy were tested for detection thresholds (cold, warm, and mechanical) in both the forearm and foot, as well as for heat pain… CONTINUE READING

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