Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta‐Analysis

  title={Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta‐Analysis},
  author={Laveena Munshi and Lorenzo Del Sorbo and Neill K. J. Adhikari and Carol L. Hodgson and Hannah Wunsch and Maureen O. Meade and Elizabeth Uleryk and Jordi Mancebo and Antonio Pesenti and Marco Vito Ranieri and Eddy Fan},
  journal={Annals of the American Thoracic Society},
Rationale: The application of prone positioning for acute respiratory distress syndrome (ARDS) has evolved, with recent trials focusing on patients with more severe ARDS, and applying prone ventilation for more prolonged periods. Objectives: This review evaluates the effect of prone positioning on 28‐day mortality (primary outcome) compared with conventional mechanical ventilation in the supine position for adults with ARDS. Methods: We updated the literature search from a systematic review… 

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Ventilation in the prone position significantly reduced overall mortality in patients with severe acute respiratory distress syndrome andufficient duration of prone positioning was significantly associated with a reduction in overall mortality.

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