Promyelocytic leukaemia zinc finger maintains self-renewal of male germline stem cells (mGSCs) and its expression pattern in dairy goat testis.

@article{Song2013PromyelocyticLZ,
  title={Promyelocytic leukaemia zinc finger maintains self-renewal of male germline stem cells (mGSCs) and its expression pattern in dairy goat testis.},
  author={Wencong Song and Haijing Zhu and Menghui Li and Na Li and J-h Wu and Hailong Mu and Xiaotong Yao and Wei Han and Weishuai Liu and Jinlian Hua},
  journal={Cell proliferation},
  year={2013},
  volume={46 4},
  pages={457-68}
}
OBJECTIVES Previous studies have shown that promyelocytic leukaemia zinc finger (PLZF) is a spermatogonia-specific transcription factor in the testis, required to regulate self-renewal and maintenance of the spermatogonia stem cell. Up to now, expression and function of PLZF in the goat testis has not been known. The objectives of this study were to investigate PLZF expression pattern in the dairy goat and its effect on male goat germline stem cell (mGSC) self-renewal and differentiation… CONTINUE READING

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