Promyelocytic HL60 cells express NADPH oxidase and are excellent targets in a rapid spectrophotometric microplate assay for extracellular superoxide.

Abstract

A great number of drugs, toxicants, and growth factors induce the generation of intermediary reactive oxygen species (ROS). The human promyelocytic leukemia HL60 cell line differentiated along the macrophage or neutrophil lineage is a model system that is frequently used for the generation of ROS by various agents. As a primary source of ROS the superoxide… (More)

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@article{Teufelhofer2003PromyelocyticHC, title={Promyelocytic HL60 cells express NADPH oxidase and are excellent targets in a rapid spectrophotometric microplate assay for extracellular superoxide.}, author={Olga Teufelhofer and R Weiss and W. Schmidt - Parzefall and Rolf Schulte-Hermann and Michael Micksche and Walter Berger and Leonilla Elbling}, journal={Toxicological sciences : an official journal of the Society of Toxicology}, year={2003}, volume={76 2}, pages={376-83} }