Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro

  title={Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro},
  author={Oh Sang Kwon and Hyun Keol Pyo and Youn Jin Oh and Ji Hyun Han and Se Rah Lee and Jin Ho Chung and Hee Chul Eun and Kyu Han Kim},
  journal={Journal of Korean Medical Science},
  pages={283 - 289}
Minoxidil induces hair growth in male pattern baldness and prolongs the anagen phase. All-trans retinoic acid (ATRA) has been reported to act synergistically with minoxidil in vivo: they can enhance more dense hair regrowth than either compound alone. We evaluated the effect of minoxidil combined with ATRA on hair growth in vitro. The effect of co-treatment of minoxidil and ATRA on hair growth was studied in hair follicle organ culture. In cultured human dermal papilla cells (DPCs) and normal… 

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  • 2000
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