Promotion of recovery from thoracic spinal cord contusion in rats by stimulation of medullary raphe or its midbrain input.

@article{Hentall2012PromotionOR,
  title={Promotion of recovery from thoracic spinal cord contusion in rats by stimulation of medullary raphe or its midbrain input.},
  author={Ian D. Hentall and Melissa M Carballosa Gonzalez},
  journal={Neurorehabilitation and neural repair},
  year={2012},
  volume={26 4},
  pages={374-84}
}
BACKGROUND . Brainstem regions with descending axons could influence recovery after spinal cord injury, thus presenting potential targets for treatment. Neurons in the hindbrain raphe magnus respond to sensory and chemical concomitants of trauma (eg, pain, circulating cytokines) and release trophic substances (serotonin, neuropeptides) in widespread spinal regions. OBJECTIVES . The authors tested in rats whether intermittent stimulation of the raphe magnus or its major midbrain input, the… CONTINUE READING