Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52

@inproceedings{Gaines2015PromotionOP,
  title={Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52},
  author={William A. Gaines and Stephen K. Godin and Faiz F. Kabbinavar and T. Swamy Rao and Andrew P Vandemark and Patrick Sung and Kara A Bernstein},
  booktitle={Nature communications},
  year={2015}
}
The conserved budding yeast Rad51 paralogues, including Rad55, Rad57, Csm2 and Psy3 are indispensable for homologous recombination (HR)-mediated chromosome damage repair. Rad55 and Rad57 are associated in a heterodimer, while Csm2 and Psy3 form the Shu complex with Shu1 and Shu2. Here we show that Rad55 bridges an interaction between Csm2 with Rad51 and Rad52 and, using a fully reconstituted system, demonstrate that the Shu complex synergizes with Rad55-Rad57 and Rad52 to promote nucleation of… CONTINUE READING
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A new protein complex promoting the assembly of Rad51 filaments

  • H Sasanuma
  • Nat. Commun
  • 2013

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