Promotion of evolution by intracellular coexistence of mutator and normal DNA polymerases.

@article{Aoki2001PromotionOE,
  title={Promotion of evolution by intracellular coexistence of mutator and normal DNA polymerases.},
  author={Ken-ichi Aoki and Mitsuru Furusawa},
  journal={Journal of theoretical biology},
  year={2001},
  volume={209 2},
  pages={
          213-22
        }
}
The efficient evolution of a population requires both genetic diversity and stable reproduction of advantageous genotypes. The accuracy of DNA replication guarantees the stable reproduction, while errors during DNA replication produce the genetic diversity. Thus, one key to the promotion of evolution is inherent in DNA replication. In bacteria, replication forks progress bidirectionally from the single origin of replication on a genome. One replication fork contains two DNA polymerase molecules… CONTINUE READING

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