Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein.

@article{Zhang1992PromotionOA,
  title={Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein.},
  author={X M Zhang and Dennis H Stamp and Salomon Minkin and Alan Medline and Denis E. Corpet and Walter R. Bruce and Michael C. Archer},
  journal={Journal of the National Cancer Institute},
  year={1992},
  volume={84 13},
  pages={1026-30}
}
BACKGROUND We have previously shown that thermolyzed protein (casein) cooked with fat in the diet of the rat promotes the growth of aberrant crypt foci (putative precursors of colon cancer) assessed at 100 days. PURPOSE To determine how thermolysis affects this promotion, we examined thermolysis conditions, quantity of thermolyzed protein in the diet, and duration of thermolysis. To determine whether the previous finding of promotion of aberrant crypt foci corresponds to promotion of cancers… CONTINUE READING

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An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2009
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Dehydroalanine and lysinoalanine in thermolyzed casein do not promote colon cancer in the rat.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2008
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