Promotion of Cellular Growth and Motility Is Independent of Enzymatic Activity of Fibroblast Activation Protein-α.

Abstract

BACKGROUND Fibroblast activation protein-alpha (FAPα) is a type-II integral membrane serine protease and is expressed in most stromal fibroblasts. Recent studies showed that FAPα is also expressed in certain cancer cells but its role is still uncertain. MATERIALS AND METHODS We analyzed the non-enzymatic activity of FAPα in breast cancer cells by… (More)

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Cite this paper

@article{Lv2016PromotionOC, title={Promotion of Cellular Growth and Motility Is Independent of Enzymatic Activity of Fibroblast Activation Protein-α.}, author={Baobei Lv and Fei Xie and Pengxiang Zhao and Xuemei Ma and Wen Jiang and Jing Yu and Xiaodong Zhang and Jun Jia}, journal={Cancer genomics & proteomics}, year={2016}, volume={13 3}, pages={201-8} }